| S 320 CDI (220.026, 220.126) 3.2 Дизель | OM 613.960 | 197 | 1999–2002 |
| S 320 CDI (220.025, 220.125) 3.2 Дизель | OM 648.960 | 204 | 2002–2005 |
| S 400 CDI (220.028, 220.128) 4.0 Дизель | OM 628.960 | 250 | 2000–2005 |
| S 400 CDI (220.028, 220.128) 4.0 Дизель | OM 628.960 | 260 | 2003–2005 |
| S 280 (220.063, 220.163) 2.8 Бензин | M 112.922 | 204 | 1998–2005 |
| S 320 (220.065, 220.165) 3.2 Бензин | M 112.944 | 224 | 1998–2005 |
| S 350 (220.067, 220.167) 3.7 Бензин | M 112.972 | 245 | 2002–2005 |
| S 350 4-matic (220.087, 220.187) 3.7 Бензин | M 112.975 | 245 | 2003–2005 |
| S 430 (220.070, 220.170) 4.3 Бензин | M 113.941 | 279 | 1998–2005 |
| S 430 4-matic (220.083, 220.183) 4.3 Бензин | M 113.948 | 279 | 2002–2005 |
| S 500 (220.075, 220.175, 220.875) 5.0 Бензин | M 113.960, M 113.966 | 306 | 1998–2005 |
| S 500 4-matic (220.084, 220.184) 5.0 Бензин | M 113.966 | 306 | 2002–2005 |
| S 55 AMG (220.073, 220.173) 5.4 Бензин | M 113.986 | 360 | 1999–2005 |
| S 55 AMG 5.4 Бензин | | 475 | 2003–2005 |
| S 55 AMG Kompressor (220.074, 220.174) 5.4 Бензин | M 113.991 | 500 | 2002–2005 |
| S 600 (220.176) 5.5 Бензин | M 275.950 | 500 | 2002–2005 |
| S 600 (220.878, 220.178) 5.8 Бензин | M 137.970 | 367 | 2000–2005 |
| S 65 AMG (220.179) 6.0 Бензин | M 275.980 | 612 | 2004–2005 |
| S 63 AMG 6.3 Бензин | M 137.980 | 444 | 2001–2005 |
